1 While AA affects both sexes and all age groups, the first onset reportedly occurs by age 40 years in more than 80% of patients and by age 20 years in 40%. ![]() The most common forms of AA include small patches of hair loss, complete loss of scalp hair (ie, alopecia totalis ), or complete loss of scalp, facial, and body hair (ie, alopecia universalis ). Further research is warranted to elucidate subpopulation differences and trends in AA in the broader US population.Īlopecia areata (AA) is an autoimmune disease characterized by nonscarring hair loss involving the scalp, face, and/or body. Prevalence and incidence of AA and AT/AU were higher among female vs male individuals, adults vs children and adolescents, and in the Northeast vs other regions.Ĭonclusions and Relevance The results of this cohort study suggest that these recent AA prevalence and incidence estimates could help improve current understanding of the disease burden. Roughly 5% to 10% of prevalent and incident cases of AA were AT/AU. National employer-sponsored insurance population estimates were obtained using population-based weights. ![]() Main Outcomes and Measures Annual incidence and prevalence rates were calculated and stratified by age, sex, and region. Incident cases were identified by 1 or more claims for AA or AT/AU during a specific year and no diagnosis the year prior. Objective To estimate the annual prevalence and incidence of AA and AT and/or AU (AT/AU) in the US.ĭesign, Setting, and Participants This retrospective, population-based cohort study was conducted from January 2016 to December 2019 and included enrollees in the IBM MarketScan Commercial Claims and Encounters and Medicare Supplemental databases and their dependents, with plan enrollment during each study calendar year and the year prior.Įxposures Prevalent cases were identified by 1 or more claims for AA or AT/AU ( International Statistical Classification of Diseases, Tenth Revision, Clinical Modification codes L63.x, L63.0, L63.1) during each year of interest or the year prior. The epidemiology of AA in the US remains unclear, having previously been extrapolated from older studies that were limited to specific geographic areas or clinical settings, or from self-reported data. Alopecia totalis (AT) and alopecia universalis (AU) involve complete loss of the scalp and body hair, respectively. ![]() Importance Alopecia areata (AA) is characterized by nonscarring hair loss of the scalp, face, and/or body. ![]() Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.
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